PSC Partners Seeking a Cure Canada

Primary sclerosing cholangitis, PSC, causes the bile ducts inside and outside the liver to become scarred, narrowed and eventually blocked. As more and more ducts are blocked, bile becomes trapped and damages the liver. The damage, if left unchecked, causes liver cell death, which leads to cirrhosis and may eventually require a liver transplant.

It is estimated that nearly 21 per 100,000 men and 6 per 100,000 women have the disease. PSC is often found in people with inflammatory bowel disease (IBD), most often ulcerative colitis (UC) and sometimes Crohn's disease. Over 75 percent of PSC patients have ulcerative colitis. PSC is also associated with other autoimmune diseases.

There are medications and procedures that can help relieve some aspects of the disease and symptoms, but the only definitive treatment is a liver transplant.

PSC Partners Seeking a Cure Canada is a registered Canadian charity with CRA business number 811905165RR0001. We are an independently-run public foundation and legally affiliated with PSC Partners Seeking a Cure, a 501(c)3 nonprofit foundation. We’re serious about finding a cure for PSC, and your contribution will bring us closer to our goal. Thank you!

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